Latour was a jointly held lord's domain until the end of the 16th century, whose co-owners received rents from the farmers who cultivated the land. At that time, the property was not entirely covered by vines and yet production largely exceeded requirements. There was no proper storage for the wine and it had to be drunk within the year. The estate remained in the hands of the Mullet family until the late 17th century, and while direct use of the land gradually replaced the leasing system, the wine-making situation changed very little.
As a result of successive marriages and inheritances, Château Latour became the property of Alexandre de Ségur, who quickly acquired a considerable collection of properties in the Médoc. The château's real wine history began with the arrival of this family. Just before his death in 1716, Alexandre de Ségur acquired Château Lafite. His son, Nicolas-Alexandre, was dubbed the « Prince of the Vines » by Louis XV. President of the Parliament of Bordeaux, he further enlarged the family's estates in 1718 with the acquisition of plots from Mouton and Calon.